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Elena Flowers

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Open access Oct 2026

Temporal dysregulation of PPARG-PRKAG2 co-localization in gray matter: Implications for cognitive decline and intervention targets in type 2 diabetes.

PPARG-mediated metabolic remodeling and PRKAG2/AMPK-driven energy sensing may act as neuroprotective mechanisms in response to both pathological (T2DM) and normative (aging) contexts, potentially resulting in cognitive decline and increased risk for dementia.

S. Kesler, K. Lewis, Heather E. Cuevas et al. · 0 citations

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