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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

Elena Navarro-Guerrero

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Open access Oct 2026

Ubiquitin chain editing promotes p97/VCP-dependent removal of RPA from DNA.

DNA repair requires dynamic control of proteins on single-stranded DNA (ssDNA), yet how ubiquitin signaling regulates ssDNA-bound factors remains poorly understood. Here, we identify in human cells a ubiquitin chain-editing mechanism that promotes extraction of replication protein A (RPA) from ssDNA. We show that RPA s...

Matthew T. Drake, Xian-Zhen Zhou, Alexandra McStea et al. · 0 citations
Open access Aug 2026

Selective quality control of mistargeted mitochondrial proteins at the endoplasmic reticulum

It is shown that mitochondrial import stress drives widespread rerouting of mitochondrial proteins to the endoplasmic reticulum (ER), with strong enrichment for hydrophobic oxidative phosphorylation (OXPHOS) components.

Y. Tsuchiya, Nikita Sergejevs, M. E. Dueñas et al. · 0 citations

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