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Author

Elham Hoveizi

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Open access Oct 2026

CRISPR/Cas9‐Mediated Correction of the SLC25A38 Mutation in a Patient With Sideroblastic Anemia

ABSTRACT Background The SLC25A38 is one of the genes of the heme biosynthesis pathway and disruptive alterations therein cause autosomal recessive congenital sideroblastic anemia (CSA). Primary patient‐derived fibroblasts can be used as a valuable source for disease modeling, cell therapy studies, and the generation of...

S. Yazdanparast, H. Galehdari, S. Khatami et al. · 0 citations
Aug 2026

SLC25A38 gene modification mediated by CRISPR/Cas9 in HEK293T cell line.

It is reported that the choice of sgRNA target site affects its targeted cleavage activity and show that the combination of guideRNA with SpCas9 can effectively delete the exonic fragment of the SLC25A38 gene in HEK293T cells.

S. Yazdanparast, Hamid Galehdari, S. Khatami et al. · 1 citation

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