Review
Open access
Oct 2026
Early-Onset Colorectal Cancer: Molecular Features, Risk Stratification, Screening Gaps, and Personalized Prevention
Although overall colorectal cancer (CRC) incidence and mortality have declined with widespread screening, early-onset CRC (EOCRC), defined as diagnosis before age 50, continues to rise. EOCRC partially differs from late-onset CRC (LOCRC) in clinical presentation, molecular features, polyp characteristics, and patterns...
Vanessa Lu, Fiona Xu, G. Graziosi et al.
· Gastroenterology Insights · 0 citations