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Elie Lambert

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Open access Oct 2026

Kinetic decoupling of early transcription reveals Mediator regulates paused RNA polymerase II stability

The Mediator complex has been established as an essential coactivator for RNA polymerase II (RNAPII) transcription initiation, yet its potential role in regulating promoter-proximal pausing and Positive transcription elongation factor b (P-TEFb) recruitment has remained unresolved. Investigating these highly dynamic pr...

Elie Lambert, Christian Poitras, François Robert · 0 citations

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