Author

Elisa Del Savio

h-index 4 View on Semantic Scholar

We have 2 of 7 papers

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Open access Aug 2026

Histone deacetylase activity limits the response to EZH2 inhibition-based therapy in epithelioid sarcoma and is targetable by epigenetic combination

Findings identify failure to accumulate H3K27 acetylation as a hallmark of resistance to EZH2 inhibition-based treatment, and show that pharmacological HDAC inhibition can restore this chromatin transition and re-sensitize resistant tumors, providing a rationale for combined epigenetic targeting strategies in INI1-defi...

N. Arrighetti, C. Soffientini, V. Zuco et al. · bioRxiv · 1 citation

Open access Jul 2026

TWIST1 bridges p53 and MDM2 and impairs the efficacy of MDM2 inhibitors

Targeting TWIST1 restores p53 pathway activation and sensitizes sarcoma cells to MDM2 blockade, establishing TWIST1 as a promising predictive biomarker and therapeutic vulnerability for improving MDM2i efficacy.

S. Piccinin, Bernadetta Szaboova, Flavia Pivetta et al. · Journal of experimental & cl... · 0 citations