Open access
Sep 2026
Multimodal Imaging of Hypoxia, Metabolism and pH in Feline Sarcoma Using Hyperpolarized 13C MRI and PET
ABSTRACT Direct in vivo characterization of the interplay between tumor hypoxia, acidosis, and metabolic reprogramming remains a major translational challenge. Here, we establish a clinically deployable simultaneous PET/MRI workflow on a clinical 3 T system that combines hyperpolarized 13C MRI of [1‐13C]pyruvate to map...
Martin Grashei, Tanja Groll, S. Kahl et al.
· Advancement of science · 0 citations