Association of tumor mutational burden and tumor-infiltrating lymphocytes with second primary cancer after complete resection of non-small cell lung cancer
Introduction The risk of developing second primary cancers (SPC) after complete surgical resection of non-small cell lung cancer (NSCLC) has been estimated at 1-2% per patient-year. We investigated whether tumor genomic instability, assessed by tumor mutational burden (TMB), and host immune response, assessed by tumor-...