Elizaveta M. Zhernikova

Nondirected Palladium-Catalyzed C(sp3)-H Oxygenation with H2O2.

Palladium(II) complexes of the TPA family (TPA = tris(2-pyridylmethyl)amine) catalyze selective C(sp3)-H oxyfunctionalizations but have so far been unable to activate "green" oxidant H2O2, instead requiring peroxycarboxylic acids (2-4 equiv, best results coming with m-CPBA). Herein, we show that hydrogen peroxide itsel...