Ellen J. Pritham

Escape of the BC200 gene to a human poxvirus reveals its persistent transposition in primates.

Although BC200 was co-opted approximately 40 million years ago to regulate neuronal translation, it is shown that it never lost its mobilization capacity and functioned as a "master" source of L1-mediated germline retrotransposition events throughout anthropoid evolution, spawning hundreds of lineage-specific insertion...