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Author

Elsa C. Y. Yan

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Open access Aug 2026

First Hydration Shell Integrity: Key to Protein Stability

A molecular model guided by the application of chiral-selective vibrational sum frequency generation spectroscopy to a solvated protein concludes that protein stability directly correlates with first hydration shell integrity.

Zhi-Jie Wang, Matthew Tremblay, Nicholas Hatzis-Schoch et al. · 0 citations
Open access Jul 2026

Chain Collapse, Reduced Dielectric, and Water Release Drive Protein Phase Separation.

Biomolecular condensates represent unique microenvironments that organize intracellular biology and promote biochemical reactions. However, the biomolecular interactions driving condensate phase separation are often weak, transient, and heterogeneous. Investigating the structural biology and chemical properties of cond...

Ethan A. Perets, Jacob A. Spies, Justin H. Cheong et al. · 0 citations

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