Author

Elżbieta Płuciennik

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Open access Oct 2026

TFAP2E Expression Is Associated with Survival and a Transcriptomic Pattern in Ovarian Serous Carcinoma, Supported by Hallmark and Protein-Level Characterization

Simple Summary TFAP2E, encoding the AP-2ε transcription factor, remains poorly characterized in cancer despite the established regulatory importance of the AP-2 family. This study first evaluated tumor–normal expression differences across a pan-cancer spectrum to prioritize ovarian serous carcinoma for investigation, a...

D. Kołat, Julia Gałęziewska, Paulina Buczek et al. · Cancers · 0 citations

Review Open access Sep 2026

Parasites and allergies: a complex bidirectional relationship from evolutionary origins to modern therapeutics

Parasites and allergic diseases are linked by a complex, bidirectional relationship shaped by long-term host–parasite coevolution. This review discusses how different parasites may either promote or attenuate allergic responses through immunological, epithelial, and microbiome-mediated mechanisms. IgE-mediated immunity...

Kacper Packi, D. Świerczewski, Sylwia Klimczak et al. · Antonie van Leeuwenhoek · 0 citations

Open access Aug 2026

ATM inhibition potentiates the anticancer activity of pyrazolo[4,3-e]tetrazolo[1,5-b][1,2,4]triazine sulfonamides in colorectal cancer cells in vitro

The results indicate that MM compounds exhibit measurable anticancer activity in 3D spheroid models and that their combination with ATM inhibition modulates both viability and spheroid morphology, as reflected by changes in ATP levels, core size, and diffusion parameters.

M. Kciuk, Katarzyna Wanke, M. Mojzych et al. · Scientific Reports · 0 citations