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Author

Emily E. Steffke

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2 papers indexed here

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Open access Oct 2026

Chemotherapy enhances cancer vaccine efficacy and expands stem-like TCF1+CD8+ T cells.

Therapeutic cancer vaccines are increasingly tested in clinical settings alongside standard-of-care treatments that often include chemotherapy, yet whether chemotherapy synergizes with cancer vaccines remains unclear. Here, we tested heterologous prime-boost viral vector vaccines in combination with various chemotherap...

Laurine Noblecourt, Amanda Wicki, Ashwin K. Jainarayanan et al. · 0 citations
Open access Sep 2026

A novel sulfatide analog recognized by human iNKT cells enhances polyfunctional antigen-specific CD8+ T cell responses

Invariant natural killer T (iNKT) cells are CD1d‐restricted T cells that recognize lipid antigens. Studies of analogs of a prototypic iNKT cell antigen, α‐galactosylceramide (α‐GalCer), have shown that ceramide structure affects the activities of mouse iNKT cells recognizing the antigen. However, the impact of antigen...

Ayaka Hara, Julia DiSapio, Morgan Coombs et al. · 0 citations

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