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Emily G. Armbruster

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Open access Oct 2026

A bifunctional RNase H protein supports DNA replication and transcription in nucleus-forming Chimalliviridae phages

Jumbo bacteriophages of the Chimalliviridae family replicate their genomes within a proteinaceous phage nucleus that spatially segregates viral DNA replication and transcription from translation. While the phage nucleus protects viral DNA from host defenses, it also imposes unique constraints on genome replication and...

Phoolwanti Rani, Niklas Klusch, Shannon M. Barret et al. · 0 citations

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