Emma M. Sydir

Components of an ESCRT-independent nuclear envelope assembly pathway.

In many cells, the nuclear envelope (NE) must be reassembled after mitosis, and holes in the nuclear membrane must be sealed. During NE assembly, the NE-specific adaptor, Cmp7, recruits/activates endosomal sorting complex required for transport (ESCRT)-III proteins to mediate NE sealing. However, recent evidence sugges...