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En-Hui Lu

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Review Open access Oct 2026

Acetylation–ubiquitination crosstalk in NLRP3–gasdermin pyroptosis: a substrate-state framework with relevance to ulcerative colitis

Acetylation and ubiquitination regulate inflammatory cell death, but evidence that they act together in ulcerative colitis (UC) remains limited. This review examines their interactions in nucleotide-binding oligomerisation domain-, leucine-rich repeat- and pyrin domain-containing protein 3 (NLRP3) and gasdermin D (GSDM...

Yuan-Yang Zhao, Xiao-Jie Zhu, En-Hui Lu et al. · 0 citations

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