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Review Open access Aug 2026

hNET-targeted [18F]MFBG PET as baseline functional imaging in newly diagnosed neuroblastoma

Rationale [18F]meta-fluorobenzylguanidine ([18F]MFBG) is an human norepinephrine transporter (hNET)-targeted PET tracer that has shown superior lesion detection than [123I]MIBG SPECT in patients with relapsed or refractory neuroblastoma. Its value in newly diagnosed patients, however, has not been well established. We...

Li-Feng Zhang, Xin-Hui Su, Xin-Yue Zheng et al. · 0 citations
Sep 2026

Delivery of CAR T Cells in a Magnesium-Functionated Hydrogel Boosts Peritoneal Metastasis Treatment.

Chimeric antigen receptor (CAR) T cells show limited efficacy in solid tumors due to suppressive factors in the tumor microenvironment. In this study, we identified extracellular magnesium (Mg2+) as a pharmacologically modulable regulator of CAR T activity. Mg2+ supplementation increased early activation and augmented...

Jun-Lin Li, Xu-Tao Liu, En Ren et al. · 0 citations

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