Structural and biochemical analysis of the IBV nsp15 endoribonuclease reveals the necessity of peripheral site residues for activity
Infectious bronchitis virus (IBV) is a member of the Gammacoronavirus genus responsible for respiratory illness and weakened eggshells in infected chickens, adversely impacting the poultry industry. Escaping innate immune detection during infection is crucial for coronavirus proliferation in the host. The production of...