Open access
Sep 2026
KMT2E recruitment by H3 serotonylation regulates neurodevelopmental chromatin dynamics
Histone H3 Gln 5 serotonylation (H3Q5ser) is a recently identified epigenetic modification in brain that modulates reader interactions with adjacent H3 Lys 4 trimethylation (H3K4me3) to promote transcriptional permissiveness1,2. However, whether H3K4me3Q5ser and its associated binding proteins regulate neurodevelopment...
Jennifer C. O'Chan, Benjamin H. Weekley, Ce-Li Yang et al.
· bioRxiv · 0 citations