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Review Open access Aug 2026

Heart Failure with Reduced versus Preserved Ejection Fraction: Molecular Mechanisms, Immunologic Pathways, Current Therapies, and Future Directions

Heart failure remains a major clinical and public health challenge due to its rising prevalence, heterogeneous biology, and persistent burden of morbidity, mortality, and healthcare utilization. Although left ventricular ejection fraction remains central to classification and treatment selection, it incompletely captur...

Eri Kim, Devendra K. Agrawal · 1 citation

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