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Eric P. Jacobo

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Sep 2026

AQP4 Extended Region Binds to α-Syntrophin with a Novel Binding Motif.

Aquaporin-4 (AQP4) is an integral membrane protein channel specific for water molecules. It is highly polarized in the endfeet of astrocytes in the central nervous system where it allows water-ion homeostasis. AQP4 has two N-terminal isoforms: M1 (long) and M23 (short). Both isoforms retain their function but differ in...

Eric P. Jacobo, Michael J. Martinez, Barbara Barile et al. · 0 citations

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