Author

Erica J. Washington

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Open access Jul 2026

Trehalose-6-phosphate synthase promotes thermotolerance by governing glycolytic flux in Cryptococcus deneoformans

This study uncovers a previously unappreciated mechanism of Tps1-mediated heat adaptation in C. deneoformans, by revealing that Tps1 functions as a critical metabolic gatekeeper that safeguards glycolytic flux to sustain growth at elevated temperatures.

V. Yadav, Kahlia A. Carl, J. Heitman et al. · bioRxiv · 0 citations