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Erika Gabriela Guido Ávila

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Open access Sep 2026

Bioequivalence Assessment of Sitagliptin/Metformin Extended-Release Fixed-Dose Combinations in Healthy Mexican Subjects Under Fasting and Fed Conditions

Background/Objectives: Management of Type 2 Diabetes (T2D) frequently requires combination therapy. Fixed-dose combinations (FDCs) of sitagliptin and extended-release (ER) metformin improve therapeutic adherence but pose biopharmaceutical challenges related to matrix robustness and food–drug interactions. This study ev...

Omar Emmanuel Hernández Piña, Porfirio de la Cruz-Cruz, Erika Gabriela Guido Ávila et al. · 0 citations

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