Ernesto Bernal Mizrachi

In-utero exposure to maternal hyperinsulinemia impacts glucose homeostasis in male offspring transiently

Abstract Fetal in-utero exposures are known to impact the long-term metabolic health of offspring. Insulin is the primary treatment to manage glucose concentrations in mothers with gestational diabetes. However, adverse offspring outcomes persist, such as macrosomia and increased risk of early obesity in offspring with...