Open access
Sep 2026
WDR82 code coordinates transcription and pre-mRNA 3′-end processing through regulated phosphorylation
Phosphorylation plays a central role in coordinating transcription with pre-mRNA maturation, yet the mechanistic understanding of how transcription is regulated by phosphorylation remains limited. The PP1 phosphatase removes Cdk9-dependent phosphorylation of Pol II and Spt5, triggering transcription termination. Here...
Alex Au, Abigail Southers, Krzysztof Kuś et al.
· Nature Communications · 0 citations