Chronic insomnia is characterized by reduced sleep duration and is associated with substantial physical and psychological morbidity. Existing treatments are limited by accessibility, tolerability, and persistent residual symptoms. Given emerging evidence implicating the cerebellum in sleep–wake regulation, we evaluated...
Feng-Yi Hao, Sandra Zhong, Roger C. Ho et al.· Research Square· 0 citations
Memory consolidation during sleep depends on the precisely timed coordination of hippocampal reactivation with cortical slow oscillations and spindles. In humans this coupling has been characterised correlationally, while causal investigations have required intracranial stimulation in restricted patient cohorts or used...
Prince Okyere, Jun-Heng Li, Tobias Raufeisen et al.· bioRxiv· 0 citations
Abstract Parkinson's disease (PD) is a progressive multisystem disorder in which motor and non-motor symptoms impair quality-of-life. High-frequency transcranial pulsed current stimulation (tPCS) modulates network-level dysfunction and may serve as an adjunct therapy in PD. In a randomized controlled trial, 38 particip...
Zheng Li, Sandra Zhong, Lan Wang et al.· Research Square· 0 citations
We present the Generalized Activating Function (GAF), a biophysics-grounded framework that accelerates neural activation predictions by up to three orders of magnitude relative to NEURON simulations of multi-compartment cable models while maintaining high predictive accuracy (
R
2
= 0.99). By overcoming computa...
Taylor H. Newton, Javier García Ordóñez, Abdallah Alashqar et al.· Communications Biology· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.
