Review
Open access
Sep 2026
Targeting amino acid biosynthesis pathways for antibacterial drug discovery: Chemical lessons and design opportunities.
This review examines bacterial amino acid metabolism through a medicinal chemistry lens, focusing on prioritized and emerging enzyme targets with meaningful inhibitor development, structure-activity relationship (SAR), cellular activity, or target validation.
Ahmed E. Ibrahim, Amatus Salam, N. A. Wani et al.
· European journal of medicina... · 0 citations