Open access
Sep 2026
Functional and Compositional Shifts in Lung and Gut Microbiota after One Year of Treatment with Highly Effective CFTR Modulators in Cystic Fibrosis.
BACKGROUND Highly effective CFTR modulator therapy with elexacaftor-tezacaftor-ivacaftor (ETI) has revolutionized clinical outcomes in cystic fibrosis (CF), yet its effects on gut and lung microbiota, especially at the functional level, are poorly understood. METHODS In a 12-month prospective study, we enrolled 35 cl...
N. Bastón-Paz, C. García-Durán, Doĝukan Bayraktar et al.
· Archivos de Bronconeumologia · 0 citations