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Author

Ethan L. Ostrom

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2 papers indexed here

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Open access Oct 2026

Mitochondrial oxidative stress in skeletal muscle alters metabolic signaling responses to acute muscle contraction.

Activation of redox-sensitive signal transduction cascades is an increasingly appreciated mechanism of exercise adaptation in skeletal muscle. Aging and disease are associated with altered redox homeostasis, potentially altering redox responses to muscle contraction, and adaptations to exercise. It is unclear how chron...

Ethan L. Ostrom, Aurora Mattson-Hughes, James McDonald et al. · 0 citations
Review Aug 2026

Exercise and Phytochemicals as Modulators of Redox Homeostasis in Aging.

Reduced resilience to physiological stress, including impaired redox signaling, is a hallmark of aging that contributes to chronic disease risk. The transcription factor Nrf2 is widely considered a master regulator of redox homeostasis. Although exercise is a potent activator of Nrf2 signaling, exercise-induced Nrf2 ac...

T. Traustadóttir, H. Islam, Ethan L. Ostrom · 0 citations

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