Open access
Sep 2026
Novel enantiopure pyridine-based aminoalcohols as promising antimalarial candidates.
Malaria is the fifth deadliest parasitic infection in the world. Herein, three new series of pyridine-based amino alcohols including twenty compounds were designed and synthesized using a short and optimized asymmetric synthetic route. Following in vitro evaluation of their activity against Pf3D7 and PfW2 strains and a...
A. Herrero, C. Tisnerat, Guillaume Bentzinger et al.
· European journal of medicina... · 0 citations