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Author

Eugene C. Yi

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Open access Oct 2026

The developmental dopamine trajectory hypothesis of ADHD across the lifespan

Attention-deficit/hyperactivity disorder (ADHD) is increasingly recognized as a lifespan neurodevelopmental disorder, yet the mechanisms underlying its changing clinical presentation across development remain poorly understood. Although childhood ADHD is typically characterized by hyperactivity, impulsivity, and inatte...

R. J. Custodio, Stephan Getzmann, E. Wascher et al. · 0 citations
Review Open access Sep 2026

Neurodevelopmental reward dysregulation and addiction risk in ADHD.

Attention-deficit/hyperactivity disorder (ADHD) is associated with an elevated risk of substance use disorders (SUDs), yet most affected individuals do not develop addiction, indicating that vulnerability is selectively distributed rather than intrinsic to the disorder itself. This Review synthesizes current evidence o...

R. J. Custodio, Eugene C. Yi, Bung-Nyun Kim et al. · 0 citations

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