Eun Young Kim

TLR4 signaling cascades leading to increases in albumin permeability, nephrin ectodomain shedding, and apoptosis in MPC‐5 podocytes

Abstract Proteinuria is a cardinal symptom of kidney disease, but common transient proteinurias may reflect a normal physiological response to distant tissue damage or infection. Here we observed that activation of Toll‐like receptor‐4 (TLR4) using the selective agonist CRX572 induced three distinct functional effects...