Author

EunAh Lee

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Open access Aug 2026

PKM2 Inhibitors Induce Autophagic Cell Death Through Suppression of PKM2-Mediated Glycolysis in Cisplatin-Resistant Ovarian Cancer Cells

Findings indicate that PKM2 overexpression plays a central role in cisplatin resistance in ovarian cancer, and targeting PKM2 with inhibitors such as shikonin or compound 3K may represent a promising strategy to overcome chemoresistance and improve therapeutic outcomes in patients with advanced ovarian cancer.

Hae-Eun Park, Haeun Lee, Ju Ri Kim et al. · International Journal of Mol... · 0 citations

Open access Jul 2026

Targeting HDAC6 mitigates diabetic nephropathy through modulation of oxidative stress, inflammatory pathways, and apoptotic signaling.

It is demonstrated that HDAC6 inhibition exerts potent renoprotective effects and represents a promising therapeutic strategy for diabetic nephropathy.

U. Kim, EunAh Lee, Ju Ri Kim et al. · Biochemical Pharmacology · 0 citations