EP1102 - ECE_2948 - The inflammasome machinery is dysregulated and represents a therapeutic vulnerability in pituitary tumours causing Cushing's disease
A clinically relevant inflammasome-associated molecular dysregulation in ACTHomas is demonstrated and specific components are identified as discriminant biomarkers and actionable therapeutic targets, providing a strong rationale for repurposing inflammasome inhibition as a precision-oriented therapeutic strategy in Cus...