Author

Éva Varga

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Open access Aug 2026

flexiAsCas12a and other Cas12a variants enhance the applicability of Cas12a nucleases in prime editing

FlexiAsCas12a joins the repertoire of Cas12a PAM variants, enabling access to an increasing number of target sequences by Cas12a nucleases, and expands the range of recognized PAM sequences by Cas12a variants to include NATN, NCCN and GTCN sequences.

Éva Varga, Luca Gál, Krisztina Huszár et al. · Genome Biology · 0 citations