Lysosomal Expression Profile in Plasma Associates with Disease Severity in Parkinson's Disease.
BACKGROUND Parkinson's disease (PD) is a clinically and biologically heterogeneous neurodegenerative disorder, driven by multiple mechanisms among which are lysosomal and mitochondrial dysfunction. Here, we explored blood-based lysosomal and mitochondrial profiles in relation to PD diagnosis and severity. METHODS Pla...