Open access
Aug 2026
Cohort studies may underestimate rare vaccine adverse events: evidence from stroke incidence following COVID-19 vaccination.
BACKGROUND The self-controlled case series (SCCS) design is widely used for short-term vaccine safety assessment but allows only indirect estimation of absolute risk differences. This study evaluated whether absolute measures should be estimated exclusively using cohort designs by comparing excess stroke incidence foll...
H. Chemaitelly, Naveed Akhtar, S. Al Jerdi et al.
· Expert Review of Vaccines · 0 citations