Discovery of dihydrothiazolo ring-fused 2-pyridones with extended carboxylic acid as anti-influenza A agents.
The identification of a series of dihydrothiazolo-ring-fused 2-pyridones bearing an extended carboxylic acid motif as promising antiviral scaffolds are reported, establishing the extended carboxylic-acid 2-pyridone scaffold as a strong foundation for advancing both targeted anti-influenza A agents and broader-spectrum...