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F. Barkhof

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Review Open access Aug 2026

SWI versus T2*GRE for ARIA-H monitoring: a pragmatic perspective on adoption in clinical practice.

Although radiological severity thresholds for amyloid-related imaging abnormalities with hemosiderin deposition (ARIA-H) were developed using 2-dimensional acquisitions of T2*-weighted gradient-recalled echo (T2*GRE) MRI in pivotal anti-amyloid trials, adoption of well established 3D susceptibility-weighted imaging (SW...

Meike W. Vernooij, T. G. Oliveira, Roland Wiest et al. · 0 citations
#artificial intelligence Open access Sep 2026

Artificial Intelligence-Based Detection of ARIA on MRI During Alzheimer Disease Therapy: Expert Opinion on Responsible Clinical Integration.

Amyloid-targeted monoclonal antibody therapies have introduced a new era in the treatment of early Alzheimer disease. However, their use has increased the importance of detecting and monitoring amyloid-related imaging abnormalities (ARIA) on MRI, as such findings may influence treatment continuation, dose modification,...

J. Petrella, F. Barkhof, T. Benzinger et al. · 0 citations
Open access Aug 2026

Diffuse glioma perfusion quantification with ASL and DSC: a head-to-head comparison with 15O-H2O PET

While neither ASL nor DSC is fully comparable to 15O-H2O PET in all tumors, ASL presents a viable non-invasive alternative to DSC for glioma imaging and the findings encourage future studies to investigate the extent to which the combination of ASL and DSC can measure complementary tumor hemodynamics.

J. Petr, N. Verburg, J. Kuijer et al. · 0 citations

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