Open access
Aug 2026
Cell senescence emerges as a hallmark and therapeutic target of chronic intracellular infection
Intracellular pathogens are ideal candidates for modelling the pathophysiology of chronic infection, as they hide within host cells and avoid immune clearance by reshaping cellular fate. This study unveils how the intracellular pathogen Mycobacterium abscessus (Mab) reprograms alveolar macrophages towards a senescent s...
E. Scarpa, D. Oliveri, D. Rondelli et al.
· Nature Communications · 0 citations