Author

F. Doğu

3 papers indexed here

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Review Open access Aug 2026

Nuclear Factor Kappa B (NF-κB)1 and NF-κB2 Deficiency: An Unpredictable Defect With Wide Clinical and Immunologic Phenotype.

The Nuclear Factor Kappa B (NF-kB) signalling pathway is essential for regulating inflammation, cell survival, and adaptive immune responses through its canonical (NF-κB1-associated) and noncanonical (NF-κB2-associated) branches. The canonical pathway mediates rapid and broad reactions to immune stimuli, whereas the no...

Selin Sevinç, Candan Islamoğlu, Şule Haskoloğlu et al. · Scandinavian Journal of Immu... · 0 citations

Open access Aug 2026

Clinical spectrum and survival outcomes of malignancies in pediatric patients with inborn errors of immunity

Early immunologic evaluation and timely, individualized consideration of HSCT may support optimized management in children and adolescents, in whom cancer may be the first manifestation of IEI.

Nazli Deveci Demirbas, Z. Haskoloğlu, Tutku Baylan et al. · Frontiers in Immunology · 0 citations

Case report Aug 2026

A novel FLNA p.Pro2469Ser variant is associated with impaired T and NK cell function and immune dysregulation

Findings indicate that the FLNA p.Pro2469Ser variant identified in a pediatric patient presenting with recurrent infections and inflammatory manifestations is associated with altered immune-cell signaling, disturbed cortical cytoskeletal organization, and immune dysregulation.

Ş. Erdem, A. Kısaarslan, M. B. Acar et al. · Immunologic research · 0 citations