Author

F. Golab

3 papers indexed here

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Open access Sep 2026

Identification of Key Genes and Pathways in Parkinson’s Disease Through Bioinformatics Analysis

Integrative transcriptomics identified conserved central-peripheral signatures in PD and five hub genes are candidate biomarkers/therapeutic targets, offering a systems-level framework for disease mechanisms and independent cohort validation.

Ehsan Lotfi, Arsh Ketabforoush, Fereshteh Azeditehrani et al. · Bioinformatics and Biology I... · 0 citations

Review 2026

Non-coding RNAs related to PD1/PD-L1 signaling with potential diagnostic, prognostic, and therapeutic value in the tumorigenesis of brain cancers

Brain cancers are among the most aggressive malignancies associated with significant global morbidity and mortality. Cancer immunotherapy has emerged as a promising novel approach for the treatment of brain cancer through regulating the PD-1/PD-L1 signaling and disrupting tumor immune escape. Several targeted therapies...

Reihane Behnam-Rassouli, Farzaneh Entezari, Majid Ghorbanzadeh et al. · Iranian Journal of Basic Med... · 0 citations

Review Aug 2026

Mechanisms of Resistance to Immune Checkpoint Inhibitors and Therapeutic Strategies to Overcome Them: An Integrative Review.

Immune checkpoint inhibitors (ICIs) targeting PD-1, PD-L1, CTLA-4, and LAG-3 have transformed cancer therapy, but resistance limits durable benefit. This integrative review summarizes primary, adaptive, and acquired resistance driven by tumor-intrinsic defects, suppressive tumor microenvironmental programs, and host-re...

Ehsan Lotfi, F. Golab · Cancer Investigation · 0 citations