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Open access Sep 2026

β‐Caryophyllene Mitigates Thioacetamide‐Induced Liver Fibrosis Through CB2‐Mediated Suppression of Necroptosis: A Therapeutic Investigation

ABSTRACT β‐Caryophyllene (BCP), a selective agonist of cannabinoid receptor type 2 (CB2), has garnered attention as a promising nutraceutical agent for modulating organ damage. The current study aimed at evaluating the pharmacological role of BCP in Thioacetamide (TAA)‐induced liver fibrosis, with particular attention...

Lujain Bader Eddin, Seenipandi Arunachalam, Loay Lubbad et al. · 0 citations
Aug 2026

Eucalyptol Mitigates Isoproterenol-Induced Myocardial Injury in Rats via Activation of p38 MAPK/JNK Signaling, Suppression of ER Stress, and Modulation of Apoptotic Pathway.

BACKGROUND Myocardial injury (MI), a subset of cardiovascular diseases, remains a leading cause of deaths globally, driven by pathological inflammation, oxidative stress, and apoptotic cell death. Despite advances in interventional cardiology, high relapse rates and therapeutic limitations underscore the urgent need fo...

Bushra Zia, M. Meeran, S. Azimullah et al. · 0 citations

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