Aug 2026
A sonogenetic antigen-presenting nanoplatform enables spatiotemporal control of calcium signalling in T cells for enhanced cancer immunotherapy.
In B16-F10 melanoma-bearing mice, sonogenetic aAPC promotes tumor infiltration and proliferation of CD8+ T cells, reduces immunosuppressive cells, and significantly suppresses tumor growth without eliciting adverse systemic immune-related events.
Qing Zhao, Wushuang Gong, Xuesha Xing et al.
· Biomaterials · 0 citations