Author

F. Mendonça

2 papers indexed here

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Open access Sep 2026

Dual antileishmanial and immunoregulatory activities of synthetic chalcones against Leishmania braziliensis.

Leishmaniasis remains a neglected tropical disease with limited therapeutic options and significant drug toxicity. In this study, two synthetic chalcones, (E)-1-(benzo[d][1,3]dioxol-5-yl)-3-(4-dimethylaminophenyl)prop-2-en-1-one (FER42) and (E)-1-(benzo[d][1,3]dioxol-5-yl)-3-(4-fluorophenyl)prop-2-en-1-one (FER45), wer...

Rebeca Pinheiro de Jesus Santana, Beatriz Cerqueira dos Santos, D. Silva et al. · Microbial Pathogenesis · 0 citations

Open access Aug 2026

In Vitro and In Silico Evaluation of the Potentiating Effect of Thiadiazine Derivatives Against Multidrug-Resistant (MDR) Bacterial Strains

Although the evaluated thiadiazine derivatives lacked direct antibacterial activity, they significantly enhanced the efficacy of antibiotics against multidrug-resistant bacteria.

E. D. da Silva, I. G. P. Dantas, Matheus dos Santos Lourenço et al. · Antibiotics · 0 citations