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F. Nemavhola

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Review Open access Aug 2026

Post-MI Remodeling Mechanics of Left Ventricle: Microstructure-Informed Models, Identifiability, and Uncertainty for Patient-Specific Prediction

Background: Myocardial infarction (MI) causes spatially heterogeneous loss of contractility and progressive extracellular matrix remodeling, altering left ventricular mechanics from the acute phase through chronic remodeling. This review integrates current understanding of infarct, border-zone, and remote-myocardial mi...

T. Pandelani, F. Nemavhola · 0 citations
Open access Aug 2026

GRAIL-heart: A graph attention network for inferring ligand-receptor interactions in spatial transcriptomics

GRAIL-Heart is presented, a graph-attention-based framework that integrates spatial tissue topology with multi-task learning to predict context-dependent L-R interactions, reconstruct gene expression, and infer causal signalling pathways in spatial transcriptomics data.

Tumo Kgabeng, Lu-Lu Wang, H. Ngwangwa et al. · 0 citations

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