KDM6B interacts with nucleo-adhesome components CSRP2 and TGFB1I1 to regulate EMT
The methyltransferase EZH2 (Enhancer of Zest Homolog 2) and the demethylase KDM6B (Lysine Demethylase 6B) have been associated with epithelial to mesenchymal transition (EMT) and poor prognosis in various cancers(1–9). These enzymes methylate and demethylate H3K27me3 and regulate distinct sets of genes controlling EMT...