Author

F. Puglisi

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Open access Oct 2026

Age-specific patterns in colorectal cancer incidence and survival over time: a 17-year population-based cancer registry study from northeastern Italy.

BACKGROUND Age-specific differences in colorectal cancer remain insufficiently characterized in studies integrating incidence and survival dynamics. AIMS We analyzed age-specific patterns of colorectal cancer incidence and survival over time using population-based registry data from northeastern Italy, including 16,7...

M. Taborelli, F. Toffolutti, T. Angelin et al. · Digestive and Liver Disease · 0 citations

Open access Sep 2026

CDK12/13 inhibition overcomes platinum resistance by impairing RNA metabolism

Epithelial ovarian cancer (EOC) is a highly lethal disease characterized by a high rate of platinum (PT)-resistant recurrence. Dysregulation of transcriptional and alternative splicing (AS) has been suggested as a possible mechanism of PT resistance involving transcriptional cyclin-dependent kinases (CDKs). We report t...

Ilenia Pellarin, Valentina Rossi, R. Margiotta et al. · Signal Transduction and Targ... · 0 citations

Open access Aug 2026

Ten-year survival of women with invasive breast cancer by stage, molecular subtype, and grade combined: a population-based study

Abstract Background Stage at diagnosis, histologic grade, and molecular subtypes are established prognostic indicators for women with breast cancer (BC), but their impact on population-based survival estimates is poorly documented. This study assessed long-term BC survival trends according to these factors. Methods We...

Fabiola Giudici, D. Serraino, F. Puglisi et al. · The Oncologist · 0 citations