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Open access Oct 2026

Mitochondrial carrier SLC25A34 links clock, diet, and temperature control of adipocyte lipid cycling.

Adipocyte lipid metabolism is coordinated by circadian rhythms, diet, and environmental temperature, but how these diverse signals are molecularly integrated remains unknown. We showed that these cues converge on the orphan mitochondrial transporter SLC25A34 to orchestrate lipid cycling. During the sleep phase, the adi...

I. Karavaeva, A. Basse, S. Trammell et al. · 3 citations
Open access Sep 2026

A single dorsal vagal complex circuit mediates the aversive and anorectic responses to GLP1R agonists.

GLP-1 receptor agonists (GLP1RAs) effectively reduce feeding to treat obesity, although nausea and other aversive side effects of these drugs can limit their use. Brainstem circuits that promote satiation and mediate the physiological control of body weight can be distinguished from those that cause aversion. It remain...

Warren T. Yacawych, Yi Wang, Guo-Xian Zhou et al. · 0 citations

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