Loss of MSH6 or MSH2 sensitizes progressive glioblastoma to radiotherapy
<strong>A prime resistance mechanism of glioblastoma to temozolomide is a vulnerability to radiation therapy</strong>
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<strong>A prime resistance mechanism of glioblastoma to temozolomide is a vulnerability to radiation therapy</strong>
It is demonstrated that integrated multimodal tumor profiling can inform personalized maintenance treatment decisions and that chemotherapy reshapes tumor cell diversity.
The results showed that psychological distress, depression, and protein carbonyl content decreased significantly by discharge, and cortisol levels and telomere length showed no significant changes, demonstrating the feasibility of integrating psychological and molecular data to investigate biological response following...
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